Haemagglutination test utilizing pathogenic Treponema pallidum for the sero-diagnosis of syphilis.
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منابع مشابه
Haemagglutination test utilizing pathogenic Treponema pallidum for the sero-diagnosis of syphilis.
Haemagglutination reactions for the diagnosis of syphilis were first reported by Blumenthal (1932) and Bachmann (1932), who used an extract of syphilitic liver as the antigen. However, the test yielded both false positive and false negative reactions, rendering it of no diagnostic value. An agglutination test with suspensions of Reiter treponemes was used for testing cerebrospinal fluid by Roem...
متن کاملTreponema pallidum specific IgM haemagglutination test for serodiagnosis of syphilis.
The Treponema pallidum specific IgM haemagglutination (TP-IgM-HA) test uses erythrocytes sensitised with antiserum to human IgM to separate IgM from IgG in serum. Specific antitreponemal IgM captured in this way is detected by adding a second reagent comprising erythrocytes sensitised with T pallidum antigen. Eighty two serum samples from 82 patients with untreated syphilis, 521 samples from 73...
متن کاملTreponema pallidum haemagglutination test as a screening procedure for the diagnosis of syphilis.
The serological diagnosis of syphilis relies upon the widespread use of non-specific screenig tests, such as the cardiolipin Wassermann reaction (CWR) and the Venereal Diseases Research Laboratory (VDRL) slide test, in combination with the Reiter protein complement-fixation (RPCF) test (British Cooperative Clinical Group, 1972). Where necessary, the fluorescent treponemal antibody-absorbed (FTA...
متن کاملAppraisal of the Treponema pallidum haemagglutination test.
Several attempts have been made to use haemagglutination reactions for the diagnosis of syphilis between 1932 and 1958. The first reliable method was developed by Rathlev (1965). Further results of investigations with this method have been reported by authors from Japan and from the Venereal Disease Research Laboratory in Atlanta, U.S.A. Rathlev prepared the reagents for the test in the Statens...
متن کاملTreponema pallidum haemagglutination test for syphilis. Evaluation of a modified micro-method.
Passive haemagglutination of erythrocytes sensitized with antigen is an extremely sensitive method for the detection of antibody. Its application to the serological diagnosis of syphilis was first reported by Rathlev (1965, 1967), using a haemagglutination technique for the detection of specific antitreponemal antibody in which formolized tanned sheep cells sensitized with ultrasonicated materi...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1967
ISSN: 1368-4973
DOI: 10.1136/sti.43.3.181